Bioinformatics in structural genomics.
نویسندگان
چکیده
منابع مشابه
5th International Scientific Conference of “Plant Genetics, Genomics, Bioinformatics, and Biotechnology” (24-29 June 2019, Novosibirsk, Russia)
This article has no abstract. DOI: 10.18502/jfqhc.6.1.458
متن کاملBioinformatics in structural genomics - Editorial
Editorial BIOINFORMATICS IN STRUCTURAL GENOMICS The goals of structural genomics initiatives are to significantly expand the structural 'coverage' of sequence space. A number of specific objectives have been included within this broad definition. These include, the determination of the detailed three-dimensional structure for at least one representative of each protein fold that occurs in natur...
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MOTIVATION Structural genomics eventually aims at determining structures for all proteins. However, in the beginning experimentalists are likely to focus on globular proteins to achieve a rapid basic coverage of protein sequence space. How many proteins will structural genomics have to target? How many proteins will be excluded since we already have structural information for these or since the...
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SUMMARY The structural genomics of histone tail recognition web server is an open access resource that presents within mini articles all publicly available experimental structures of histone tails in complex with human proteins. Each article is composed of interactive 3D slides that dissect the structural mechanism underlying the recognition of specific sequences and histone marks. A concise te...
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A large number of structural genomics programmes have been established worldwide with the common aim of large-scale, high-throughput protein structure determination. Due to the considerable challenges posed by the experimental methods of structural determination (primarily X-ray crystallography and nuclear magnetic resonance spectroscopy) it is important to select and prioritise candidate molec...
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عنوان ژورنال:
- Bioinformatics
دوره 18 7 شماره
صفحات -
تاریخ انتشار 2002